Micro Biosystems

Bioengineering based on micro/nano fabrications and measurements: Biophysics of motor proteins, biomechanics in Micro Total Analysis Systems (μTAS) and Organ-on-a-Chip (Microphysiological Systems)

Yokokawa group focuses on the development of innovative micro/nano-fabricated devices (microfluidic devices) with applications in medicine, pharmacology and biology. Central to our vision is to promote the synergy effect in our group. It will deepen our understandings of various biological functions and mechanisms at the micro/nano-scale in an interdisciplinary research milieu by converging engineering, life sciences, and physical sciences. It will contribute to provide solutions for the improvement of quality of life (QOL) and treatment/diagnosis of diseases by personalized medicine in the globally. The group is committed to the achievement of the intellectual vision through organs-on-a-chip (micro-physiological systems) and biophysics of motor proteins.

Academic Staff

* Add "kyoto-u.ac.jp" to each E-mail address.

Ryuji YOKOKAWA

Professor (Graduate School of Engineering)

Research Interests

  1. Organ-on-a-Chip (Microphysiological Systems) for kidney physiological functions
  2. Perfusable on-chip vascular network for mechanobiology and organogenesis applications
  3. Biophysics of motor proteins on micro/nano-fabricated substrates

Contacts

Room c2S16, Building C3, Katsura Campus
TEL: +81-75-383-3680
E-mail: yokokawa.ryuji.8c@

Kazuya FUJIMOTO

Associate Professor (Graduate School of Engineering)

Research Interests

My research interest is to collaborate nano-micro phenomena and information technology for measurement and manipulation of biomaterials like proteins and cells.

Contacts

Room c2N06, Building C3, Katsura Campus
TEL: +81-75-383-3687
E-mail: fujimoto.kazuya.2m@

Satomi Matsumoto

Assistant Professor (Graduate School of Engineering)

Research Interests

1.  Development and functional evaluation of vascularized Liver-on-a-Chip models
2.  Analysis of hepatocyte–non-parenchymal cell interactions in regulating metabolic and inflammatory responses, and optimization of three-dimensional co-culture conditions
3.  Application of three-dimensional liver models to disease modeling, including metabolic dysfunction–associated steatohepatitis (MASH) and liver fibrosis

Contacts

Room c2N06, Building C3, Katsura Campus
TEL: +81-75-383-3687
E-mail: matsumoto.satomi.7j@

Ma Cheng

Project-Specific Assistant Professor (Graduate School of Engineering)

Research Interests

- Development and application of  Organ-on-a-Chip model using human iPSC-derived kidney organoids
- Construction and analysis of kidney disease models using patient-derived iPS cells
- Development and application of microphysiological systems for the analysis of biological functions

Contacts

Room c2N06, Building C3, Katsura Campus
TEL: +81-75-383-3687
E-mail: ma.cheng.5z@